個人簡介:
劉成扣,南京工業(yè)大學(xué)副教授,碩士生導(dǎo)師,南京工業(yè)大學(xué)生物與制藥工程學(xué)院制藥工程系副主任。以綠色化學(xué)為主要研究方向,以微化工技術(shù)為代表的過程強化技術(shù)為研究中心,開展了微化工技術(shù)與電催化、光催化、微泡或微波等多外力場耦合研究,實現(xiàn)多個醫(yī)農(nóng)藥中間體等精細(xì)化學(xué)品的連續(xù)合成。主持國家自然科學(xué)基金青年基金及中國博士后科學(xué)基金面上項目等。以通訊或第一作者在Chem Sci、Green Chem、ACS Sustain Chem Eng、Org lett等發(fā)表SCI論文28篇;以主要發(fā)明人申請國家發(fā)明專利26項,授權(quán)21項。
代表性成果:
1. Zhang, J.-M.; Liu, C.-K.; Qiao, Y.-Q.; Wei, M.-H.; Guan, W.-J.; Mao, Z.-R.; Qin, H.; Fang, Z.; Guo, K., Intramolecular trapping of spiro radicals to produce unusual cyclization products from usual migration substrates. Chemical Science 2023, DOI: 10.1039/D2SC05768A.
2. Guan, W.-J.; Ying, K.; Yuan, C.-C.; Hang, J.-L.; Liu, C.-K.; Huang, X.-X.; Fang, Z.; Guo, K., Catalyst- and oxidant-free electrooxidative site-selective 3/4+2 annulation to fused polycyclic heteroaromatics. Green Chemistry 2022, 24, 5191-5196.
3. Liu, C.-K.; Lin, Y.; Cai, C.; Yuan, C.-C.; Fang, Z.; Guo, K., Continuous-flow electro-oxidative coupling of sulfides with activated methylene compounds leading to sulfur ylides. Green Chemistry 2021, 23, 2956-2961.
4. Liu, C.-K.; Chen, M.-Y.; Lin, X.-X.; Fang, Z.; Guo, K., Catalyst- and oxidant-free electrochemical para-selective hydroxylation of N-arylamides in batch and continuous-flow. Green Chemistry 2020, 22, 6437-6443.
5. Cai, C.; Lu, Y.; Yuan, C.-C.; Fang, Z.; Yang, X.-B.; Liu, C.-K.; Guo, K., Metal-free C-C cross coupling: Electrosynthesis of azaheterocycles through anodic oxidation cyclization of 1,6-enynes. ACS Sustainable Chemistry & Engineering 2022, 10, 3288-3294.